Serum estradiol-17 beta as determined by mass fragmentography and by radioimmunoassay.
نویسندگان
چکیده
We describe the preparation of [2,4,16,16-2H4]estradiol-17 beta. The method for quantitative determination of subpicomole amounts of estradiol-17 beta (trimethylsilyl ether derivatives) by gas-liquid chromatography-mass spectrometry with multiple ion detector and with [2H4]estradiol-17 beta as the carrier is presented and characterized. Values for serum samples, as measured by radioimmunoassay and by mass fragmentography, agreed well.
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 24 4 شماره
صفحات -
تاریخ انتشار 1978